120205-48-3
- Product Name:(3R,4S,5S)-tert-butyl 3-Methoxy-5-Methyl-4-(MethylaMino)heptanoate hydroc hloride
- Molecular Formula:C14H29NO3.ClH
- Purity:99%
- Molecular Weight:295.85
Product Details
Purity:99%
Buy High Quality Top Purity 120205-48-3, Best Price (3R,4S,5S)-tert-butyl 3-Methoxy-5-Methyl-4-(MethylaMino)heptanoate hydroc hloride
- Molecular Formula:C14H29NO3.ClH
- Molecular Weight:295.85
- PSA:47.56000
- LogP:3.56020
120205-48-3 Relevant articles
Rational Design of Azastatin as a Potential ADC Payload with Reduced Bystander Killing
Hartmann, Rafael W.,Fahrner, Raphael,Shevshenko, Denys,Fyrkn?s, M?rten,Larsson, Rolf,Lehmann, Fredrik,Odell, Luke R.
, p. 2500 - 2512 (2020/10/20)
Auristatins are a class of ultrapotent m...
CONJUGATE OF MONOMETHYL AURISTATIN F AND TRASTUZUMAB AND ITS USE FOR THE TREATMENT OF CANCER
-
Paragraph 0279; 0280, (2017/05/15)
The present invention relates to an anti...
COMPOSITION FOR THE TREATMENT OF IGF-1R EXPRESSING CANCER
-
Page/Page column 113; 114, (2017/05/17)
The present invention relates to a metho...
CONJUGATE OF MONOMETHYL AURISTATIN F AND TRASTUZUMAB AND ITS USE FOR THE TREATMENT OF CANCER
-
Page/Page column 42, (2016/11/17)
The present invention relates to an anti...
120205-48-3 Process route
- 870640-64-5
tert-butyl (3R,4S,5S)-4-[benzyl(methyl)amino]-3-methoxy-5-methyl heptanoate
- 120205-48-3
tert-Butyl (3R,4S,5S)-3-methoxy-4-(N-methylamino)-5-methylheptanoate hydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In ethanol; water; at 20 ℃; for 18h;
|
87% |
With hydrogenchloride; palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 18h; under 760.051 Torr;
|
82% |
With hydrogenchloride; palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 18h; under 760.051 Torr;
|
82% |
With hydrogenchloride; palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 18h; under 760.051 Torr;
|
82% |
With hydrogenchloride; palladium on activated charcoal; hydrogen; In ethanol; water; at 20 ℃; for 18h; Inert atmosphere;
|
82% |
With hydrogenchloride; palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 18h;
|
82% |
With hydrogenchloride; palladium on activated charcoal; hydrogen; In ethanol; water; at 20 ℃; for 18h;
|
82% |
With hydrogenchloride; palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 18h;
|
82% |
- 120205-58-5
tert-Butyl (3R,4S,5S)-3-methoxy-4-
-5-methylheptanoate
- 120205-48-3
tert-Butyl (3R,4S,5S)-3-methoxy-4-(N-methylamino)-5-methylheptanoate hydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In methanol; for 3h; under 2327.23 Torr; Inert atmosphere;
|
92% |
tert-Butyl (3R,4S,5S)-3-methoxy-4-
With hydrogenchloride; In 1,4-dioxane; at -78 ℃; for 0.25h;
|
90% |
120205-48-3 Upstream products
-
154633-73-5
tert-Butyl (3S,4S,5S)-3-methoxy-4-
-5-methylheptanoate -
540-88-5
acetic acid tert-butyl ester
-
3160-59-6
N-Cbz-L-Isoleucine
-
120205-57-4
tert-Butyl (3S,4S,5S)-3-hydroxy-4-
-5-methylheptanoate
120205-48-3 Downstream products
-
110417-88-4
dolastatin 10
-
120205-53-0
(3R,4S,5S)-tert-butyl 4-((S)-2-((S)-2-(dimethylamino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoate
-
1438852-21-1
methyl (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoate
Relevant Products
-
3-Amino-5-methylisoxazole
CAS:1072-67-9
-
Fmoc-Lys(Mmt)-OH
CAS:159857-60-0
-
3,4-Dimethylpyrazole-5-carboxylic Acid
CAS:89831-40-3