1297613-73-0
- Product Name：(11aR)-12-Hydroxy-1,10-di(naphthalen-1-yl)-4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocine 12-oxide
- Molecular Formula：C37H27O4P
- Purity：99%
- Molecular Weight：566.593
Product Details
pd_meltingpoint:169-172℃
Purity:99%
Top Purity 99% Buy High Grade (11aR)-12-Hydroxy-1,10-di(naphthalen-1-yl)-4,5,6,7-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocine 12-oxide 1297613-73-0 Cheap Price
- Molecular Formula:C37H27O4P
- Molecular Weight:566.593
- Melting Point:169-172℃
- PKA:1.14±0.20(Predicted)
- PSA：65.57000
- Density:1.44
- LogP:9.37710
1297613-73-0 Relevant articles
SPINOL-derived phosphoric acids: Synthesis and application in enantioselective Friedel-Crafts reaction of indoles with imines
Xu, Fangxi,Huang, Dan,Han, Chao,Shen, Wei,Lin, Xufeng,Wang, Yanguang
supporting information; experimental part, p. 8677 - 8680 (2011/02/26)
A new class of chiral phosphoric acids w...
1297613-73-0 Process route
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1292849-40-1
(S)-6,6'-di(naphthalen-1-yl)-1,1'-spirobiindane-7,7'-diol
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-
1258327-08-0,1297613-73-0
(S)-6,6-di(naphthalen-1-yl)-1,1'-spirobiindane-7,7'-diyl phosphate
Conditions
| Conditions | Yield |
|---|---|
|
(S)-6,6'-di(naphthalen-1-yl)-1,1'-spirobiindane-7,7'-diol;
With
pyridine; trichlorophosphate;
at 0 - 70 ℃;
for 3h;
Inert atmosphere;
With
water;
at 0 - 110 ℃;
for 4h;
Inert atmosphere;
|
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-
(S)-7,7'-bis(1-methoxymethoxy)-1,1'-spirobiindane
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-
1258327-08-0,1297613-73-0
(S)-6,6-di(naphthalen-1-yl)-1,1'-spirobiindane-7,7'-diyl phosphate
Conditions
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 4 steps
1.1: n-butyllithium; N,N,N,N,-tetramethylethylenediamine / diethyl ether; hexane / 6 h / -78 - 20 °C / Inert atmosphere
1.2: -78 - 20 °C / Inert atmosphere
2.1: hydrogenchloride / methanol; chloroform; water / 3 h / Inert atmosphere; Reflux
3.1: 5% Pd(II)/C(eggshell); potassium carbonate / 1,4-dioxane; water / 2 h / 80 °C / Inert atmosphere
4.1: pyridine; trichlorophosphate / 3 h / 0 - 70 °C / Inert atmosphere
4.2: 4 h / 0 - 110 °C / Inert atmosphere
With
pyridine; hydrogenchloride; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; 5% Pd(II)/C(eggshell); potassium carbonate; trichlorophosphate;
In
1,4-dioxane; methanol; diethyl ether; hexane; chloroform; water;
3.1: Suzuki coupling;
|
1297613-73-0 Upstream products
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1292849-40-1
(S)-6,6'-di(naphthalen-1-yl)-1,1'-spirobiindane-7,7'-diol
-
13922-41-3
1-Naphthylboronic acid
